Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | USP2 | O75604 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | BLM | P54132 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15246474 | 0.90 | FTO (0.58) | FTOMAPTUSP2MEN1KMT2A | |
| SCHEMBL15246321 | 0.87 | FTO (0.68) | FTOMAPTUSP2MEN1KMT2A | |
| SCHEMBL22379948 | 0.84 | FTO (0.69) | FTOMAPTUSP2MEN1KMT2A | |
| SCHEMBL10260320 | 0.80 | FTO (0.76) | FTOMAPTUSP2MEN1KMT2A | |
| SCHEMBL31435692 | 0.79 | FTO (0.78) | FTOMAPTUSP2MEN1KMT2A | |
| SCHEMBL3109289 | 0.79 | FTO (0.78) | FTOMAPTUSP2MEN1KMT2A | |
| SCHEMBL21129885 | 0.79 | FTO (0.74) | FTOMAPTUSP2MEN1KMT2A | |
| SCHEMBL17972575 | 0.78 | FTO (0.77) | FTOMAPTUSP2MEN1KMT2A | |
| SCHEMBL12134945 | 0.78 | USP2 (0.60) | USP2MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL24274861 | 0.78 | FTO (0.76) | FTOMAPTUSP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822386-B1 | FOLATE RECEPTOR ALPHA BINDING LIGANDS | PURDUE RESEARCH FOUNDATION (US) | 2021-05-05 | — | — | EP | disclosed |
| US-9629918-B2 | Folate receptor alpha binding ligands | PURDUE RESEARCH FOUNDATION (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150023874-A1 | FOLATE RECEPTOR ALPHA BINDING LIGANDS | PURDUE RESEARCH FOUNDATION | 2015-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150023874-A1 | FOLATE RECEPTOR ALPHA BINDING LIGANDS | FOLR1, FOLR2, TFRC | FTO 4050/4885MAPT 2104/4885USP2 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.