Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.63 |
| ▸ | HPGDS | O60760 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | CLK1 | P49759 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906879 | 0.77 | NQO1 (1.00) | NQO1HPGDSKDM4EALDH1A1CLK1 | |
| SCHEMBL28033607 | 0.75 | ALDH1A1 (0.53) | NQO1HPGDSKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30979880 | 0.73 | HPGDS (1.00) | NQO1HPGDSKDM4EALDH1A1CLK1 | |
| SCHEMBL2201992 | 0.73 | HPGDS (1.00) | NQO1HPGDSKDM4EALDH1A1CLK1 | |
| SCHEMBL31297329 | 0.73 | HPGDS (1.00) | NQO1HPGDSKDM4EALDH1A1CLK1 | |
| SCHEMBL19355079 | 0.72 | NQO1 (0.58) | NQO1HPGDSKDM4EL3MBTL1GAA | |
| SCHEMBL28863298 | 0.72 | NQO1 (0.54) | NQO1HPGDSKDM4EALDH1A1CLK1 | |
| SCHEMBL8524163 | 0.72 | KDM4E (0.60) | NQO1HPGDSKDM4EALDH1A1CLK1 | |
| SCHEMBL2014397 | 0.72 | ALDH1A1 (0.47) | NQO1KDM4EALDH1A1GAAGLA | |
| SCHEMBL4602088 | 0.71 | KDM4E (0.61) | NQO1HPGDSKDM4EALDH1A1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098283-A1 | 3-CINNOLINECARBOXAMIDE DERIVATIVES AND THEIR USE FOR TREATING CANCER | ASTRAZENECA AB | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098283-A1 | 3-CINNOLINECARBOXAMIDE DERIVATIVES AND THEIR USE FOR TREATING CANCER | CSF3R, CSF1R, KIT | NQO1 3258/4885HPGDS 570/4885KDM4E 2188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.