Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 1.00 |
| ▸ | HPGDS | O60760 | 1/20 | 0.59 |
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | CASP7 | P55210 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21273254 | 0.82 | NQO1 (0.69) | NQO1HPGDSNCF1L3MBTL1RXFP1 | |
| SCHEMBL9945363 | 0.81 | NQO1 (0.69) | NQO1HPGDSNCF1RXFP1NPSR1 | |
| SCHEMBL21273257 | 0.81 | NQO1 (0.69) | NQO1HPGDSNCF1L3MBTL1RXFP1 | |
| SCHEMBL15761508 | 0.79 | NQO1 (0.65) | NQO1HPGDSNCF1L3MBTL1RXFP1 | |
| SCHEMBL15297243 | 0.78 | NQO1 (0.64) | NQO1HPGDSNCF1L3MBTL1RXFP1 | |
| SCHEMBL1081492 | 0.78 | NQO1 (0.64) | NQO1HPGDSNCF1L3MBTL1RXFP1 | |
| SCHEMBL4961333 | 0.78 | NQO1 (0.64) | NQO1HPGDSNCF1 | |
| SCHEMBL8002770 | 0.78 | NQO1 (0.64) | NQO1HPGDSL3MBTL1RXFP1NPSR1 | |
| SCHEMBL1640918 | 0.77 | NQO1 (0.63) | NQO1HPGDSNCF1L3MBTL1RXFP1 | |
| SCHEMBL31499214 | 0.77 | NQO1 (0.62) | NQO1HPGDSL3MBTL1RXFP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856734-B1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2025-09-24 | — | — | EP | disclosed |
| US-12065422-B2 | Reagents and process for direct C—H functionalization | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2024-08-20 | — | — | US | disclosed |
| US-12012394-B2 | Alpha-synuclein ligands | WASHINGTON UNIVERSITY (US) | 2024-06-18 | — | — | US | disclosed |
| US-20230227425-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-07-20 | — | — | US | disclosed |
| US-20230227425-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-07-20 | — | — | US | disclosed |
| US-11679168-B2 | Caspase-3-triggered molecular self-assembling PET probes and uses thereof | THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-06-20 | — | — | US | disclosed |
| US-11608322-B2 | Reagents and process for direct C—H functionalization | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-03-21 | — | — | US | disclosed |
| CN-110256342-B | Synthetic method of 2-cyano quinoline derivative | 河南省科学院化学研究所有限公司 | 2022-06-07 | — | — | CN | disclosed |
| US-20220002263-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2022-01-06 | — | — | US | disclosed |
| US-20220002263-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2022-01-06 | — | — | US | disclosed |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2007-01-18 | — | — | US | disclosed |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2007-01-18 | — | — | US | disclosed |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2007-01-18 | — | — | US | disclosed |
| WO-2006130551-A2 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006045416-A1 | QUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-04 | — | — | WO | disclosed |
| US-20060084679-A1 | Quinoline derivatives as H3R inverse agonists | HOFFMANN-LA ROCHE INC. | 2006-04-20 | — | — | US | disclosed |
| US-6329497-B1 | ANTITUMOR AGENTS; VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS | THE SCRIPPS RESEARCH INSTITUTE | 2001-12-11 | — | — | US | disclosed |
| EP-0996458-A4 | SANDRAMYCIN ANALOGS | SCRIPPS RESEARCH INST (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-0996458-A1 | SANDRAMYCIN ANALOGS | The Scripps Research Institute (US) | 2000-05-03 | — | — | EP | disclosed |
| WO-1998043663-A1 | SANDRAMYCIN ANALOGS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084679-A1 | Quinoline derivatives as H3R inverse agonists | HRH3, HRH4, HRH1 | NQO1 537/4885HPGDS 913/4885NCF1 2389/4885 |
| US-20230227425-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | CFH, DOHH, CTSH | NQO1 456/4885HPGDS 1692/4885NCF1 917/4885 |
| US-20220002263-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | CFH, DOHH, CTSH | NQO1 456/4885HPGDS 1692/4885NCF1 917/4885 |
| US-12012394-B2 | Alpha-synuclein ligands | SNCA, PARK7, LRRK2 | NQO1 909/4885HPGDS 3294/4885NCF1 1403/4885 |
| US-11679168-B2 | Caspase-3-triggered molecular self-assembling PET probes and uses thereof | CASP3, CASP14, CASP6 | NQO1 3529/4885HPGDS 2395/4885NCF1 735/4885 |
| US-11608322-B2 | Reagents and process for direct C—H functionalization | CFH, DOHH, CTSH | NQO1 544/4885HPGDS 1852/4885NCF1 936/4885 |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | NQO1 516/4885HPGDS 413/4885NCF1 91/4885 |
| US-12065422-B2 | Reagents and process for direct C—H functionalization | CFH, DOHH, CTSH | NQO1 544/4885HPGDS 1852/4885NCF1 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.