Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580587 | 0.83 | CDC7 (0.57) | CDC7SYKNPC1MAPTRAB9A | |
| SCHEMBL4327511 | 0.82 | NPC1 (0.54) | CDC7SYKNPC1MAPTRAB9A | |
| SCHEMBL15152227 | 0.80 | CDC7 (0.56) | CDC7SYKNPC1MAPTRAB9A | |
| SCHEMBL30615425 | 0.78 | MAPK1 (0.50) | CDC7SYKNPC1MAPTRAB9A | |
| SCHEMBL30728059 | 0.75 | CDC7 (0.64) | CDC7SYKNPC1MAPTRAB9A | |
| SCHEMBL8311439 | 0.74 | CDC7 (0.55) | CDC7SYKNPC1MAPTRAB9A | |
| SCHEMBL30279147 | 0.74 | CDC7 (0.55) | CDC7SYKNPC1MAPTRAB9A | |
| SCHEMBL8788646 | 0.74 | CDC7 (0.59) | CDC7SYKNPC1MAPTRAB9A | |
| SCHEMBL31735411 | 0.73 | BPTF (0.64) | CDC7TRPM5BRD4CCNCCDK8 | |
| SCHEMBL30549500 | 0.72 | TRPA1 (0.64) | BRD4CREBBPTRPA1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015011400-A1 | NOVEL PYRROLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2015-01-29 | — | — | WO | disclosed |