Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106505 | 0.81 | ALDH3A1 (0.56) | MAPK1ALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL29580587 | 0.78 | CDC7 (0.57) | MAPK1ALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL16416922 | 0.78 | CDC7 (0.51) | MAPK1ALDH1A1MAPTGAACDC7 | |
| SCHEMBL4327511 | 0.77 | NPC1 (0.54) | ALDH1A1MAPTCDC7RAB9ANPC1 | |
| SCHEMBL20772927 | 0.76 | PKM (0.63) | MAPK1ALDH1A1TDP1CASP7L3MBTL1 | |
| SCHEMBL30832833 | 0.76 | PKM (0.63) | MAPK1ALDH1A1TDP1CASP7L3MBTL1 | |
| SCHEMBL497083 | 0.76 | ALDH1A1 (0.65) | MAPK1ALDH1A1TDP1CASP7L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27767104 | 0.74 | ALDH1A1 (0.63) | MAPK1ALDH1A1TDP1CASP7L3MBTL1 | |
| SCHEMBL30615428 | 0.74 | MAPK1 (0.58) | MAPK1ALDH1A1TDP1CASP7L3MBTL1 | |
| SCHEMBL5946836 | 0.74 | HTR2A (0.50) | MAPK1ALDH1A1TDP1CASP7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |