Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23229998 | 0.83 | LOXL2 (0.51) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1253989 | 0.81 | LOXL2 (0.58) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL24197399 | 0.81 | LOXL2 (0.50) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL528996 | 0.79 | LOXL2 (0.60) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL23330383 | 0.79 | CYP1A2 (0.55) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| Bromide SCHEMBL7457488 | 0.78 | LOXL2 (0.58) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| Iodide SCHEMBL1343657 | 0.78 | LOXL2 (0.58) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL2331919 | 0.77 | LOXL2 (0.62) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL2333461 | 0.77 | LOXL2 (0.62) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL23023094 | 0.77 | GAA (0.51) | LOXL2HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940938-B2 | Michael reaction with recovery of the catalyst | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-27 | — | — | US | disclosed |