Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.45 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1253989 | 0.84 | LOXL2 (0.58) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3265308 | 0.83 | LOXL2 (0.49) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL19563549 | 0.82 | HTR1A (0.53) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1040581 | 0.81 | LOXL2 (0.55) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL16418000 | 0.81 | LOXL2 (0.55) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL30331546 | 0.81 | GAA (0.50) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL24197400 | 0.81 | GAA (0.50) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL15826444 | 0.80 | S1PR2 (0.52) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL17260150 | 0.79 | SLC2A1 (0.52) | LOXL2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6155906 | 0.78 | LOXL2 (0.55) | LOXL2HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346769-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | UNIVERSIDAD DE GRANADA (ES) | 2023-11-02 | — | — | US | disclosed |
| US-20230346769-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | UNIVERSIDAD DE GRANADA (ES) | 2023-11-02 | — | — | US | disclosed |
| EP-4180039-A1 | <SMALLCAPS/>? ? ?LEISHMANIA? ? ? ? ?USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS | Universidad de Granada (ES) | 2023-05-17 | — | — | EP | disclosed |
| EP-4180039-A1 | <SMALLCAPS/>? ? ?LEISHMANIA? ? ? ? ?USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS | Universidad de Granada (ES) | 2023-05-17 | — | — | EP | disclosed |
| WO-2022008784-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | UNIVERSIDAD DE GRANADA (ES) | 2022-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346769-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | SRM, SMS, ARG2 | LOXL2 1254/4885HTR1A 3949/4885ADRA1D 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.