Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.62 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495433 | 0.87 | ALDH1A1 (0.72) | KDM4EHSD17B10ALDH1A1HTTTSHR | |
| SCHEMBL569988 | 0.86 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL22965266 | 0.86 | KDM4E (0.59) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL28287010 | 0.85 | KDM4E (0.78) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL14648187 | 0.83 | KDM4E (0.79) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL16421862 | 0.83 | GAA (0.59) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL30951936 | 0.83 | ALDH1A1 (0.64) | KDM4EHSD17B10ALDH1A1HTTTSHR | |
| SCHEMBL3976738 | 0.82 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL22965212 | 0.82 | PTGDR2 (0.59) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL29427371 | 0.82 | TSHR (0.55) | KDM4EHSD17B10ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |
| WO-2015011331-A1 | USE OF COMPOUNDS DERIVED FROM PYRIDAZINO[1',6':1,2]PYRIDO[3,4-B]INDOLE AND PYRIDAZINO[3,2-B]BENZIMIDAZOLE SALTS AS ANTI-INFLAMMATORY AGENTS | FUNDACIÓN PARA LA INVESTIGACIÓN BIOMÉDICA DEL HOSPITAL UNIVERSITARIO LA PAZ (FIBHULP) (ES) | 2015-01-29 | — | — | WO | disclosed |