Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 3/20 | 0.53 |
| ▸ | ALPL | P05186 | 2/20 | 0.53 |
| ▸ | ALPG | P10696 | 2/20 | 0.53 |
| ▸ | ALPP | P05187 | 1/20 | 0.53 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495433 | 0.84 | ALDH1A1 (0.72) | ALDH1A1KDM4ETSHRLMNAHTT | |
| SCHEMBL18955316 | 0.84 | KDM4E (0.62) | ALDH1A1KDM4ETSHRLMNAHTT | |
| SCHEMBL16421959 | 0.83 | KDM4E (0.73) | ALDH1A1KDM4ETSHRLMNAHTT | |
| SCHEMBL5547090 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4EHTTHSD17B10SMN1; SMN2 | |
| SCHEMBL2686518 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4ETSHRLMNAHSD17B10 | |
| SCHEMBL3587930 | 0.79 | KDM4E (0.69) | ALDH1A1KDM4ETSHRLMNAHTT | |
| SCHEMBL19714470 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRLMNAHTT | |
| SCHEMBL24744761 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4ETSHRLMNAHTT | |
| SCHEMBL24774224 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRLMNAHTT | |
| SCHEMBL30952847 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4ETSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123195-A1 | TARGETED PROTEIN DEGRADATION USING PRODRUGS OF BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2024-06-13 | — | — | WO | disclosed |