Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.59 |
| ▸ | FAAH | O00519 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16421862 | 0.96 | GAA (0.59) | PTGDR2FAAHHTTLMNATP53 | |
| SCHEMBL22965266 | 0.91 | KDM4E (0.59) | PTGDR2HTTLMNATP53KDM4E | |
| SCHEMBL540948 | 0.87 | FAAH (0.57) | PTGDR2FAAHHTTLMNATP53 | |
| SCHEMBL9430801 | 0.85 | PTGDR2 (0.55) | PTGDR2FAAHHTTLMNAKDM4E | |
| SCHEMBL3003332 | 0.85 | PTGDR2 (0.55) | PTGDR2FAAHHTTTP53KDM4E | |
| SCHEMBL7745965 | 0.85 | SMN1; SMN2 (0.58) | PTGDR2FAAHLMNATP53KDM4E | |
| SCHEMBL7741979 | 0.84 | FAAH (0.56) | PTGDR2FAAHHTTLMNATP53 | |
| SCHEMBL22965215 | 0.84 | LMNA (0.60) | HTTLMNATP53KDM4ETNF | |
| SCHEMBL8268109 | 0.83 | PTGDR2 (0.53) | PTGDR2FAAHHTTLMNATP53 | |
| SCHEMBL540852 | 0.83 | LMNA (0.59) | FAAHHTTLMNATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161409-A1 | METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS | POLYPLUS TRANSFECTION (FR) | 2023-08-31 | — | — | WO | disclosed |
| EP-4234609-A1 | METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS | PolyPlus Transfection (FR) | 2023-08-30 | — | — | EP | disclosed |
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |