SCHEMBL16424809

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16424805	0.91	HTR3E (0.39)	HTR3EHTR3BHTR3AHTR3DHTR3C
	SCHEMBL16423058	0.87	C5AR1 (0.41)	GNRHRPTPN11PIK3CBPIK3CDPIK3CG
	SCHEMBL16423386	0.85	GNRHR (0.38)	GNRHRALDH1A1PTPN11CYP1A2CYP2D6
	SCHEMBL16423553	0.84	GNRHR (0.33)	GNRHRPTPN11
	SCHEMBL16422615	0.83	KMT2A (0.38)	GNRHRALDH1A1MEN1CYP1A2CYP2D6
	SCHEMBL16425107	0.82	MLYCD (0.38)	GNRHRALDH1A1MEN1CYP1A2CYP2D6
	SCHEMBL16422753	0.81	ALDH1A1 (0.41)	GNRHRALDH1A1MEN1CYP1A2CYP2D6
	SCHEMBL16434853	0.81	C5AR1 (0.39)	GNRHRPIK3CBPIK3CDPIK3CGPIK3CA
	SCHEMBL16422966	0.81	MEN1 (0.44)	GNRHRALDH1A1MEN1CYP1A2TSHR
	SCHEMBL16423100	0.81	MEN1 (0.39)	GNRHRALDH1A1MEN1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.