Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | FAAH | O00519 | 5/20 | 0.51 |
| ▸ | NAAA | Q02083 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439273 | 0.90 | LMNA (0.58) | ALDH1A1FAAHNAAAL3MBTL1HSD11B1 | |
| SCHEMBL4404820 | 0.83 | NPC1 (0.58) | FAAHNAAAL3MBTL1POLBMAPT | |
| SCHEMBL16425193 | 0.83 | ALDH1A1 (0.45) | ALDH1A1FAAHNAAAUSP2POLB | |
| SCHEMBL14156333 | 0.78 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBMAPTTDP1 | |
| SCHEMBL16425199 | 0.78 | MAPT (0.60) | ALDH1A1L3MBTL1POLBMAPTSMN1; SMN2 | |
| SCHEMBL11377517 | 0.76 | HSD17B10 (0.67) | ALDH1A1FAAHNAAAUSP2GAA | |
| SCHEMBL16337701 | 0.76 | NAAA (0.83) | ALDH1A1FAAHNAAAHSD11B1 | |
| SCHEMBL15074966 | 0.76 | ALDH1A1 (0.42) | ALDH1A1FAAHNAAAPOLBMAPT | |
| SCHEMBL643368 | 0.75 | PKM (0.70) | ALDH1A1USP2GAAL3MBTL1HSD11B1 | |
| SCHEMBL6428172 | 0.75 | BCHE (0.50) | ALDH1A1L3MBTL1HSD11B1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318806-A4 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-01-21 | — | — | EP | claimed |
| EP-1318806-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-06-18 | — | — | EP | claimed |
| WO-2002024197-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-03-28 | — | — | WO | claimed |
| EP-1318806-A4 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-01-21 | — | — | EP | disclosed |
| EP-1318806-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024197-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-03-28 | — | — | WO | disclosed |