Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425791 | 0.95 | MAPT (0.53) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4332253 | 0.87 | MAPT (0.46) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL13927210 | 0.86 | THRB (0.60) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL16425801 | 0.86 | THRB (0.60) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9996704 | 0.86 | THRB (0.60) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL10018716 | 0.86 | THRB (0.60) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL16425815 | 0.85 | NPC1 (0.57) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9817443 | 0.85 | RARB (0.64) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11193052 | 0.85 | RARB (0.64) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9722325 | 0.85 | MAPT (0.68) | MAPTSMN1; SMN2MEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169293-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| US-6733690-B1 | ACRYLIC ESTER POLYMERS | ROLIC AG (CH) | 2004-05-11 | — | — | US | disclosed |