Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16426757 | 1.00 | RAB9A (0.55) | RAB9ANPC1MAPTKDM4ECASP3 | |
| SCHEMBL28129799 | 0.80 | MAOB (0.43) | MAPTALDH1A1LMNACYP1A2CYP19A1 | |
| SCHEMBL16426716 | 0.77 | MAOB (0.48) | PIM1PIM2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL16427344 | 0.77 | KDR (0.49) | PIM1PIM2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL16426717 | 0.77 | MAOB (0.48) | PIM1PIM2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL16427343 | 0.77 | KDR (0.49) | PIM1PIM2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL16426515 | 0.77 | ELANE (0.43) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL27755298 | 0.77 | MAPT (0.52) | RAB9ANPC1MAPTRELAPIM1 | |
| SCHEMBL16426516 | 0.77 | ELANE (0.43) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL16442339 | 0.72 | PDGFRB (0.62) | RAB9ANPC1MAPTPIM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150038543-A1 | ANTI-GLYCATION PROPERTIES OF OXINDOLE DERIVATIVES | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-02-05 | — | — | US | disclosed |