Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.59 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.59 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16428868 | 1.00 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL16428867 | 1.00 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL17392760 | 0.86 | MCL1 (0.57) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL17392758 | 0.86 | MCL1 (0.57) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL17392755 | 0.86 | MCL1 (0.57) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL7509301 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL6278182 | 0.84 | DNM1 (0.67) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL6278183 | 0.84 | DNM1 (0.67) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL13678156 | 0.83 | APP (0.49) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL782201 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ACYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150274633-A2 | PAIN RELIEF COMPOUNDS | UNIVERSITÉ CLERMONT AUVERGNE (FR) | 2015-10-01 | — | — | US | disclosed |
| US-20150038466-A1 | PAIN RELIEF COMPOUNDS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE CLERMONT FERRAND (FR) | 2015-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038466-A1 | PAIN RELIEF COMPOUNDS | OPRL1, OPRK1, TRPV1 | ALDH1A1 1007/4885MEN1 3267/4885KMT2A 3387/4885 |
| US-20150274633-A2 | PAIN RELIEF COMPOUNDS | OPRL1, OPRK1, TRPV1 | ALDH1A1 1007/4885MEN1 3267/4885KMT2A 3387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.