Sugi Predict

Sugi Predict / Compounds / SCHEMBL1643036

SCHEMBL1643036

SCHEMBL1643036

CC(C)(C)c1cccc(-c2cccc(C(c3ccccc3)c3ccccc3)n2)c1OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FEN1 P39748 2/20 0.47
▸ ALOX5AP P20292 2/20 0.41
▸ FFAR1 O14842 1/20 0.35
▸ RXRA P19793 1/20 0.34
▸ RXRB P28702 1/20 0.34
▸ RXRG P48443 1/20 0.34
▸ PTGER1 P34995 1/20 0.33
▸ SLC6A2 P23975 1/20 0.33
▸ SLC6A4 P31645 1/20 0.33
▸ SLC6A3 Q01959 1/20 0.33
▸ BCHE P06276 1/20 0.32
▸ BRD4 O60885 2/20 0.32
▸ L3MBTL1 Q9Y468 2/20 0.31
▸ MAPT P10636 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ MRGPRX4 Q96LA9 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ MAOA P21397 1/20 0.31
▸ MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1641520 0.77 CA2 (0.42) FEN1ALOX5APSLC6A2SLC6A4SLC6A3
SCHEMBL1641585 0.76 PTGER1 (0.40) FEN1ALOX5APFFAR1RXRARXRB
SCHEMBL12766736 0.76 PTGER1 (0.40) FEN1ALOX5APPTGER1BCHEL3MBTL1
SCHEMBL1902193 0.76 FEN1 (0.44) FEN1ALOX5APRXRARXRBRXRG
SCHEMBL1643430 0.76 FEN1 (0.43) FEN1ALOX5APRXRARXRBRXRG
SCHEMBL1642995 0.76 KMT2A (0.42) FEN1ALOX5APPTGER1BCHEL3MBTL1
SCHEMBL1638313 0.72 LMNA (0.39) FEN1ALOX5APFFAR1PTGER1BRD4
SCHEMBL27866376 0.72 FEN1 (0.42) FEN1ALOX5APRXRARXRBRXRG
SCHEMBL12772154 0.70 FEN1 (0.45) FEN1ALOX5APRXRARXRBRXRG
SCHEMBL1642760 0.69 FEN1 (0.43) FEN1ALOX5APRXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546501-B2 Catalyst compounds and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-01 — — US disclosed
US-8546501-B2 Catalyst compounds and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-01 — — US disclosed
EP-2493935-A2 CATALYST COMPOUNDS AND USE THEREOF Exxonmobil Chemical Patents Inc. (US) 2012-09-05 — — EP disclosed
CN-102597016-A Catalyst compounds and use thereof EXXONMOBIL CHEM PATENTS INC 2012-07-18 — — CN disclosed
WO-2011056431-A2 CATALYST COMPOUNDS AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-05-12 — — WO disclosed
US-20110098430-A1 Catalyst Compounds and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2011-04-28 — — US disclosed
US-20110098430-A1 Catalyst Compounds and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2011-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098430-A1 Catalyst Compounds and Use Thereof OXER1, ALOX12, NOTUM FEN1 1737/4885ALOX5AP 61/4885FFAR1 337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.