Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16432142 | 0.84 | ALDH1A1 (0.69) | ALDH1A1MAPK1HIF1AHSD17B10GSK3B | |
| SCHEMBL10990106 | 0.82 | HSP90AB1 (0.61) | ALDH1A1HSD17B10ERCC5FEN1P2RX7 | |
| SCHEMBL9526213 | 0.82 | ALDH1A1 (0.71) | ALDH1A1MAPK1HIF1AGSK3BERCC5 | |
| SCHEMBL488780 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPK1HIF1AGSK3BERCC5 | |
| SCHEMBL4624113 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPK1HIF1AHSD17B10GSK3B | |
| SCHEMBL30269774 | 0.78 | HSP90AB1 (0.66) | ALDH1A1MAPK1HIF1ACA12CA1 | |
| SCHEMBL4828627 | 0.78 | HSP90AB1 (0.66) | ALDH1A1MAPK1HIF1ACA12CA1 | |
| SCHEMBL201278 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL30442360 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL17142429 | 0.77 | HSD17B10 (0.52) | ALDH1A1HSD17B10P2RX7CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532455-B1 | IMPROVED SYNTHESIS OF MONO-CHLORINATED ACETOPHENONE | SIEGFRIED AG (CH) | 2021-09-22 | — | — | EP | disclosed |
| EP-3532455-B1 | IMPROVED SYNTHESIS OF MONO-CHLORINATED ACETOPHENONE | SIEGFRIED AG (CH) | 2021-09-22 | — | — | EP | disclosed |
| US-20210107853-A1 | SYNTHESIS OF MONO-CHLORINATED ACETOPHENONE | SIEGFRIED AG (CH) | 2021-04-15 | — | — | US | disclosed |
| US-20210107853-A1 | SYNTHESIS OF MONO-CHLORINATED ACETOPHENONE | SIEGFRIED AG (CH) | 2021-04-15 | — | — | US | disclosed |
| EP-3498687-A1 | IMPROVED SYNTHESIS OF MONOCHLORINATED ACETOPHENONE | Siegfried AG (CH) | 2019-06-19 | — | — | EP | disclosed |
| EP-3498687-A1 | IMPROVED SYNTHESIS OF MONOCHLORINATED ACETOPHENONE | Siegfried AG (CH) | 2019-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107853-A1 | SYNTHESIS OF MONO-CHLORINATED ACETOPHENONE | ACACA, CYP51A1, ACACB | ALDH1A1 178/4885MAPK1 3030/4885HIF1A 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.