Sugi Predict

Sugi Predict / Compounds / SCHEMBL4828627

SCHEMBL4828627

SCHEMBL4828627

O=C(CCl)c1ccc(O)cc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSP90AB1 P08238 1/20 0.66
▸ ESR1 P03372 1/20 0.61
▸ SHBG P04278 1/20 0.61
▸ ESR2 Q92731 1/20 0.61
▸ CES2 O00748 1/20 0.59
▸ ALDH1A1 P00352 5/20 0.57
▸ CA12 O43570 3/20 0.57
▸ CA1 P00915 3/20 0.57
▸ CA2 P00918 3/20 0.57
▸ CA7 P43166 3/20 0.57
▸ CA9 Q16790 3/20 0.57
▸ CA14 Q9ULX7 3/20 0.57
▸ TSHR P16473 1/20 0.57
▸ HTT P42858 2/20 0.56
▸ GFER P55789 1/20 0.55
▸ MAPT P10636 3/20 0.54
▸ RAB9A P51151 3/20 0.54
▸ LMNA P02545 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ NPC1 O15118 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30269774 1.00 HSP90AB1 (0.66) HSP90AB1ESR1SHBGESR2CES2
SCHEMBL1091528 0.84 HTT (0.62) HSP90AB1ESR1SHBGESR2CES2
SCHEMBL29541022 0.84 HTT (0.62) HSP90AB1ESR1SHBGESR2CES2
SCHEMBL105417 0.83 HSP90AB1 (0.70) HSP90AB1ESR1SHBGESR2CES2
SCHEMBL6427459 0.83 HSP90AB1 (0.70) HSP90AB1ESR1SHBGESR2CES2
SCHEMBL7549549 0.83 HSP90AB1 (0.70) HSP90AB1ESR1SHBGESR2CES2
SCHEMBL16432142 0.82 ALDH1A1 (0.69) HSP90AB1ESR1SHBGESR2CES2
Water SCHEMBL1231468 0.81 HSP90AB1 (0.68) HSP90AB1ESR1SHBGESR2CES2
SCHEMBL29922078 0.80 MAPT (0.51) HSP90AB1ESR1SHBGESR2CES2
SCHEMBL1429602 0.80 MAPT (0.51) HSP90AB1ESR1SHBGESR2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4165029-B1 PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES DSM IP ASSETS BV (NL) 2024-07-17 — — EP claimed
EP-4165029-A1 PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES DSM IP Assets B.V. (NL) 2023-04-19 — — EP claimed
WO-2021255011-A1 PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES DSM IP ASSETS B.V. (NL) 2021-12-23 — — WO claimed
US-20060228313-A1 Method of cosmetic depigmentation care by applying at least one aurone COLETICA (FR) 2006-10-12 — — US claimed
EP-1709964-A2 A method of cosmetic depigmentation care by applying at least one aurone ENGELHARD LYON (FR) 2006-10-11 — — EP claimed
CN-115702148-B Process for the manufacture of alkylamide thiazoles 帝斯曼知识产权资产管理有限公司 2024-09-06 — — CN disclosed
EP-4165029-B1 PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES DSM IP ASSETS BV (NL) 2024-07-17 — — EP disclosed
EP-4165029-B1 PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES DSM IP ASSETS BV (NL) 2024-07-17 — — EP disclosed
EP-4165029-A1 PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES DSM IP Assets B.V. (NL) 2023-04-19 — — EP disclosed
CN-115702148-A Process for the manufacture of alkylamide thiazoles 帝斯曼知识产权资产管理有限公司 2023-02-14 — — CN disclosed
WO-2021255011-A1 PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES DSM IP ASSETS B.V. (NL) 2021-12-23 — — WO disclosed
WO-2021255011-A1 PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES DSM IP ASSETS B.V. (NL) 2021-12-23 — — WO disclosed
US-20020016472-A1 PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2002-02-07 — — US disclosed
EP-1151350-A1 PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES The Regents of the University of California (US) 2001-11-07 — — EP disclosed
WO-2000031588-A1 PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-06-02 — — WO disclosed
EP-0522000-A1 5-LIPOXYGENASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1993-01-13 — — EP disclosed
WO-1991014674-A2 5-LIPOXYGENASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1991-10-03 — — WO disclosed
EP-0113092-B1 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(4-(OXOALKYL)-1-PIPERAZINYL)-3-QUINOLINE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THEM BAYER AG (DE) 1986-05-21 — — EP disclosed
US-4547503-A 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(oxo-alkyl)-1-piperazinyl]quinoline-3-carboxylic acids and their derivatives, and antibacterial agents containing them BAYER AKTIENGESELLSCHAFT (DE) 1985-10-15 — — US disclosed
EP-0113092-A1 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(oxoalkyl)-1-piperazinyl)-3-quinoline-carboxylic acids and their derivatives, process for their preparation and antibacterial agents containing them BAYER AG (DE) 1984-07-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060228313-A1 Method of cosmetic depigmentation care by applying at least one aurone TYR, MITF, MC1R HSP90AB1 1191/4885ESR1 4524/4885SHBG 2753/4885
US-20020016472-A1 PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES ERCC4, XPA, GPX4 HSP90AB1 774/4885ESR1 3133/4885SHBG 1284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.