Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16432554 | 0.88 | ALDH1A1 (0.51) | PDGFRBKITMEN1NPC1ALDH1A1 | |
| SCHEMBL16416060 | 0.79 | MAPT (0.49) | PDGFRBKITMEN1NPC1ALDH1A1 | |
| SCHEMBL18042052 | 0.79 | DAPK3 (0.46) | KDRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29021937 | 0.77 | PDGFRB (0.47) | PDGFRBKITKDRALDH1A1 | |
| SCHEMBL2063725 | 0.76 | KMO (0.47) | ABL1PIK3CAEPHB4 | |
| SCHEMBL19311962 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MTOR | |
| SCHEMBL12096274 | 0.74 | KDM1A (0.46) | KDM1APHF8PDGFRBPAX8MEN1 | |
| SCHEMBL2063712 | 0.73 | MPL (0.50) | — | |
| SCHEMBL31546885 | 0.73 | NPC1 (0.53) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL29598549 | 0.73 | SCN4A (0.50) | KDM1APHF8PAX8KDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606035-B1 | PROCES FOR THE SYNTHESIS OF SUBSTITUTED UREA COMPOUNDS | BIAL - PORTELA & CA S A (PT) | 2017-09-06 | — | — | EP | disclosed |
| WO-2015016729-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | disclosed |