Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17819173 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16432718 | 0.90 | CD74 (0.50) | KDM4EALDH1A1MAPTFAAHMEN1 | |
| SCHEMBL17828658 | 0.90 | KDM4E (0.50) | KDM4EALDH1A1MAPTFAAHMEN1 | |
| SCHEMBL16439302 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1MAPTFAAHMEN1 | |
| SCHEMBL16433132 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1MAPTFAAHMEN1 | |
| Hydrochloric Acid SCHEMBL16433032 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1MAPTFAAHMEN1 | |
| Hydrochloric Acid SCHEMBL17819170 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1MAPTFAAHMEN1 | |
| SCHEMBL427261 | 0.86 | CHRM2 (0.53) | FAAHKMT2AMCHR1ACHESIGMAR1 | |
| SCHEMBL16432112 | 0.86 | KDM4E (0.46) | KDM4EALDH1A1MAPTFAAHMEN1 | |
| SCHEMBL428100 | 0.85 | WNK1 (0.53) | KDM4EALDH1A1MAPTFAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166560-A1 | Urea Compounds and Their Use as FAAH Enzyme Inhibitors | BIAL-PORTELA & CA, S.A. (PT) | 2016-06-16 | — | — | US | disclosed |
| WO-2015016728-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166560-A1 | Urea Compounds and Their Use as FAAH Enzyme Inhibitors | FAAH, FAAH2, HRH2 | MMP1 1408/4885MMP9 1329/4885MMP13 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.