Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16432718 | 0.93 | CD74 (0.50) | KDM4EALDH1A1MAPTMCHR1CCR5 | |
| SCHEMBL16439302 | 0.91 | KDM4E (0.47) | KDM4EALDH1A1MAPTMCHR1CCR5 | |
| SCHEMBL16439265 | 0.90 | MMP1 (0.47) | KDM4EALDH1A1MAPTMCHR1CCR5 | |
| Hydrochloric Acid SCHEMBL16433032 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1MAPTMCHR1CCR5 | |
| SCHEMBL17819173 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTMCHR1CCR5 | |
| SCHEMBL16432112 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1MAPTMCHR1CCR5 | |
| SCHEMBL428100 | 0.89 | WNK1 (0.53) | KDM4EALDH1A1MAPTMCHR1CCR5 | |
| SCHEMBL16433132 | 0.88 | KDM4E (0.44) | KDM4EALDH1A1MAPTMCHR1CCR5 | |
| SCHEMBL16439290 | 0.88 | OPRM1 (0.46) | KDM4EALDH1A1MAPTMCHR1CCR5 | |
| SCHEMBL14950181 | 0.88 | DRD2 (0.50) | MCHR1GAASIGMAR1CHRM4FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166560-A1 | Urea Compounds and Their Use as FAAH Enzyme Inhibitors | BIAL-PORTELA & CA, S.A. (PT) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166560-A1 | Urea Compounds and Their Use as FAAH Enzyme Inhibitors | FAAH, FAAH2, HRH2 | KDM4E 998/4885ALDH1A1 247/4885MAPT 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.