Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744979 | 1.00 | MYC (0.50) | MYCTRPM5CYP11B1CYP11B2NOTUM | |
| SCHEMBL14744980 | 1.00 | MYC (0.50) | MYCTRPM5CYP11B1CYP11B2NOTUM | |
| SCHEMBL21872800 | 0.81 | CYP11B1 (0.48) | MYCTRPM5CYP11B1CYP11B2NOTUM | |
| SCHEMBL30186040 | 0.81 | ALDH1A1 (0.53) | MYCTRPM5CYP11B1CYP11B2NOTUM | |
| SCHEMBL1418463 | 0.81 | ALDH1A1 (0.53) | MYCTRPM5CYP11B1CYP11B2NOTUM | |
| SCHEMBL3330747 | 0.76 | CYP11B1 (0.51) | CYP11B1CYP11B2NOTUMALDH1A1HTT | |
| SCHEMBL2450374 | 0.75 | ALDH1A1 (0.36) | MYCTRPM5CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL2450372 | 0.75 | ALDH1A1 (0.36) | MYCTRPM5CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL5563987 | 0.75 | RAB9A (0.58) | ALDH1A1HTTHPGDLMNAMAPT | |
| SCHEMBL5563991 | 0.75 | RAB9A (0.58) | ALDH1A1HTTHPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409905-B2 | Antibacterial compounds and methods for use | PTC THERAPEUTICS, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150038437-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2015-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038437-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | MRPL21, SLC11A2, CLPP | MYC 1275/4885TRPM5 3296/4885CYP11B1 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.