SCHEMBL1644585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1644321	0.86	ALDH1A1 (0.47)	TDP1L3MBTL1KMT2AMEN1ALDH1A1
	SCHEMBL1645543	0.86	THRB (0.56)	TDP1L3MBTL1KMT2AMEN1PABPC1
	SCHEMBL1644567	0.83	ALDH1A1 (0.48)	L3MBTL1KMT2AMEN1ALDH1A1MAPT
	SCHEMBL1644535	0.83	THRB (0.48)	L3MBTL1KMT2AMEN1PABPC1PDE4A
	SCHEMBL1645607	0.83	PDE4A (0.47)	KMT2AMEN1PABPC1PDE4APDE4B
	SCHEMBL1644316	0.83	THRB (0.48)	L3MBTL1KMT2AMEN1PABPC1PDE4A
	SCHEMBL1644333	0.83	THRB (0.48)	L3MBTL1KMT2AMEN1PDE4APDE4B
	SCHEMBL1646283	0.82	RAB9A (0.48)	KMT2AMEN1PABPC1PDE4APDE4B
	SCHEMBL1644307	0.78	NPC1 (0.50)	TDP1KMT2AMEN1ALDH1A1MAPT
	SCHEMBL1644501	0.78	LMNA (0.45)	L3MBTL1KMT2AMEN1PABPC1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.