Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646855 | 1.00 | FFAR1 (0.47) | FFAR1GABBR2GABBR1PTGER1PTGER4 | |
| SCHEMBL1645769 | 1.00 | FFAR1 (0.47) | FFAR1GABBR2GABBR1PTGER1PTGER4 | |
| Acetic Acid SCHEMBL1646867 | 0.96 | FFAR1 (0.45) | FFAR1GABBR2GABBR1PTGER1PTGER4 | |
| SCHEMBL28178605 | 0.84 | CYP3A4 (0.42) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL27741079 | 0.82 | GABRP (0.42) | KDM4EALDH1A1CYP2C19TSHRCYP1A2 | |
| SCHEMBL559436 | 0.79 | TSHR (0.62) | FFAR1GABBR2GABBR1PTGER1PTGER4 | |
| SCHEMBL6841260 | 0.79 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL1646939 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1TSHRHPGDHTT | |
| SCHEMBL1645936 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1TSHRHPGDHTT | |
| SCHEMBL1613850 | 0.78 | HTT (0.49) | FFAR1GABBR2GABBR1PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308829-B1 | A PROCESS FOR PREPARING R-BETA-AMINO PHENYLBUTYRIC ACID DERIVATIVES | JIANGSU HENGRUI MEDICINE CO (CN) | 2017-06-14 | — | — | EP | disclosed |
| US-8580997-B2 | Process for preparing R-beta-amino phenylbutyric acid derivatives | JIANGSU HENGRUI MEDICINE CO. LTD. (CN) | 2013-11-12 | — | — | US | disclosed |
| US-20110130587-A1 | PROCESS FOR PREPARING R-BETA-AMINO PHENYLBUTYRIC ACID DERIVATIVES | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2011-06-02 | — | — | US | disclosed |
| EP-2308829-A1 | A PROCESS FOR PREPARING R-BETA-AMINO PHENYLBUTYRIC ACID DERIVATIVES | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2011-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130587-A1 | PROCESS FOR PREPARING R-BETA-AMINO PHENYLBUTYRIC ACID DERIVATIVES | ALAD, DAO, DDO | FFAR1 975/4885GABBR2 12/4885GABBR1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.