Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646939 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HSD17B10NLRP3TSHRKDM4E | |
| SCHEMBL27618920 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HSD17B10TSHRKDM4EMEN1 | |
| SCHEMBL28866732 | 0.83 | TSHR (0.58) | ALDH1A1NLRP3TSHRMEN1KMT2A | |
| SCHEMBL27810153 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HSD17B10NLRP3TSHRKDM4E | |
| SCHEMBL8435913 | 0.81 | NLRP3 (0.45) | ALDH1A1NLRP3TSHRHTTMEN1 | |
| SCHEMBL13572960 | 0.81 | CASP1 (0.54) | ALDH1A1NLRP3TSHRHTTMEN1 | |
| SCHEMBL15968923 | 0.81 | POLB (0.48) | ALDH1A1NLRP3TSHRHTTMEN1 | |
| SCHEMBL27536950 | 0.81 | CA12 (0.45) | ALDH1A1HSD17B10NLRP3TSHRKDM4E | |
| SCHEMBL28362327 | 0.80 | TSHR (0.59) | ALDH1A1HSD17B10NLRP3TSHRKDM4E | |
| SCHEMBL1646855 | 0.78 | FFAR1 (0.47) | ALDH1A1TSHRKDM4EHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308829-B1 | A PROCESS FOR PREPARING R-BETA-AMINO PHENYLBUTYRIC ACID DERIVATIVES | JIANGSU HENGRUI MEDICINE CO (CN) | 2017-06-14 | — | — | EP | disclosed |
| US-8580997-B2 | Process for preparing R-beta-amino phenylbutyric acid derivatives | JIANGSU HENGRUI MEDICINE CO. LTD. (CN) | 2013-11-12 | — | — | US | disclosed |
| US-20110130587-A1 | PROCESS FOR PREPARING R-BETA-AMINO PHENYLBUTYRIC ACID DERIVATIVES | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2011-06-02 | — | — | US | disclosed |
| EP-2308829-A1 | A PROCESS FOR PREPARING R-BETA-AMINO PHENYLBUTYRIC ACID DERIVATIVES | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2011-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130587-A1 | PROCESS FOR PREPARING R-BETA-AMINO PHENYLBUTYRIC ACID DERIVATIVES | ALAD, DAO, DDO | ALDH1A1 1465/4885HSD17B10 800/4885NLRP3 1368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.