SCHEMBL16449652

SCHEMBL16449652

c1ccc(N2c3ccccc3N(c3ccc(-c4nc(-c5ccc(N6c7ccccc7N(c7ccccc7)c7ccccc76)cc5)nc(-c5ccc(N6c7ccccc7N(c7ccccc7)c7ccccc76)cc5)n4)cc3)c3ccccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
MAPT P10636 3/20 0.41
PDE6D O43924 1/20 0.40
MGLL Q99685 2/20 0.39
FAAH O00519 1/20 0.39
GAA P10253 2/20 0.39
ADORA2A P29274 2/20 0.39
ADORA2B P29275 2/20 0.39
ADORA1 P30542 2/20 0.39
POLB P06746 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
NTSR1 P30989 1/20 0.37
CES2 O00748 1/20 0.37
BCHE P06276 1/20 0.37
CES1 P23141 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16449665 0.98 L3MBTL1 (0.47) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL16271062 0.98 L3MBTL1 (0.47) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL16449655 0.96 L3MBTL1 (0.48) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL30409979 0.96 L3MBTL1 (0.48) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL31669 0.88 L3MBTL1 (0.45) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL20161194 0.85 L3MBTL1 (0.44) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL23181636 0.85 MEN1 (0.58) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL16449653 0.85 ALDH1A1 (0.43) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL21213103 0.85 PDE6D (0.46) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL13833020 0.85 ALDH1A1 (0.43) L3MBTL1MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-9660199-B2 Compound, light-emitting material, and organic light-emitting device KYULUX, INC. (JP) 2017-05-23 US disclosed
US-9660199-B2 Compound, light-emitting material, and organic light-emitting device KYULUX, INC. (JP) 2017-05-23 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20150041784-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND ORGANIC LIGHT-EMITTING DEVICE KYULUX, INC. (JP) 2015-02-12 US disclosed
US-20150041784-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND ORGANIC LIGHT-EMITTING DEVICE KYULUX, INC. (JP) 2015-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA L3MBTL1 251/4885MEN1 1375/4885KMT2A 1349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.