Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454899 | 0.92 | MEN1 (0.47) | MAPTMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL16454772 | 0.90 | MAPT (0.44) | MAPTMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL16454806 | 0.86 | KMT2A (0.49) | MAPTMAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL16454903 | 0.82 | ALOX15 (0.47) | MAPTMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL16454904 | 0.80 | RAB9A (0.50) | MAPTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL16454832 | 0.80 | RAB9A (0.52) | MAPTMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL16454808 | 0.80 | SMN1; SMN2 (0.49) | MAPTMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL16454893 | 0.79 | NPSR1 (0.55) | MAPTMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL16454907 | 0.78 | KDM4E (0.48) | MAPTMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL16454908 | 0.77 | ALDH1A1 (0.47) | MAPTMAPK1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015020565-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-A]PYRIDINES EXHIBITING ANTAGONIST PROPERTIES TO ADENOSINE A2A RECEPTORS, AND USE THEREOF | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НЬЮВАК" (ООО "НЬЮВАК") (RU) | 2015-02-12 | — | — | WO | disclosed |