Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | BCR | P11274 | 2/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.49 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454880 | 0.92 | MAPT (0.55) | MAPTKMT2ARAB9AIRAK4HSD17B10 | |
| SCHEMBL16454801 | 0.89 | MAPT (0.50) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL16454723 | 0.88 | AHR (0.58) | MAPTMEN1KMT2AIRAK4HSD17B10 | |
| SCHEMBL16454879 | 0.83 | IRAK4 (0.51) | MAPTKMT2ARAB9AIRAK4HSD17B10 | |
| SCHEMBL16454809 | 0.83 | TSHR (0.53) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL16454794 | 0.78 | ALDH1A1 (0.61) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL16454709 | 0.76 | SMN1; SMN2 (0.59) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL16454891 | 0.73 | NPSR1 (0.53) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL16454893 | 0.73 | NPSR1 (0.55) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL16454784 | 0.73 | TSHR (0.46) | MAPTMEN1KMT2ARAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015020565-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-A]PYRIDINES EXHIBITING ANTAGONIST PROPERTIES TO ADENOSINE A2A RECEPTORS, AND USE THEREOF | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НЬЮВАК" (ООО "НЬЮВАК") (RU) | 2015-02-12 | — | — | WO | disclosed |