Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454709 | 0.88 | SMN1; SMN2 (0.59) | AHRMAPTLMNAHSD17B10KDM4E | |
| SCHEMBL16454802 | 0.88 | MAPT (0.49) | MAPTLMNAHSD17B10IRAK4ATR | |
| SCHEMBL16454880 | 0.88 | MAPT (0.55) | AHRMAPTLMNAADORA3GMNN | |
| SCHEMBL16454801 | 0.76 | MAPT (0.50) | MAPTHSD17B10KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL16454879 | 0.74 | IRAK4 (0.51) | MAPTLMNAADORA3HSD17B10KDM4E | |
| SCHEMBL16454673 | 0.74 | ALDH1A1 (0.50) | MAPTLMNAHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL14082539 | 0.71 | MAPT (0.74) | AHRMAPTLMNAADORA3GMNN | |
| SCHEMBL4554983 | 0.71 | POLB (0.77) | AHRMAPTHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL31040567 | 0.71 | POLB (0.77) | AHRMAPTHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL16454907 | 0.70 | KDM4E (0.48) | MAPTLMNAKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015020565-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-A]PYRIDINES EXHIBITING ANTAGONIST PROPERTIES TO ADENOSINE A2A RECEPTORS, AND USE THEREOF | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НЬЮВАК" (ООО "НЬЮВАК") (RU) | 2015-02-12 | — | — | WO | disclosed |