Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18848468 | 0.94 | CTSB (0.55) | KMT2AMAPTSMN1; SMN2NPC1PIN1 | |
| SCHEMBL18043507 | 0.89 | KMT2A (0.50) | KMT2APOLBMAPTTSHRSMN1; SMN2 | |
| SCHEMBL16447123 | 0.89 | KMT2A (0.50) | KMT2APOLBMAPTTSHRSMN1; SMN2 | |
| SCHEMBL16455182 | 0.88 | KDM1A (0.53) | KMT2AMAPTSMN1; SMN2ALDH1A1TGM2 | |
| SCHEMBL16447439 | 0.85 | KMT2A (0.51) | KMT2APOLBMAPTTSHRSMN1; SMN2 | |
| SCHEMBL18848695 | 0.85 | KDM1A (0.54) | P2RY12CTSB | |
| SCHEMBL16448219 | 0.85 | KMT2A (0.51) | KMT2APOLBMAPTTSHRSMN1; SMN2 | |
| SCHEMBL18848748 | 0.83 | CTSB (0.58) | P2RY12CTSBCASR | |
| SCHEMBL18848471 | 0.82 | CTSB (0.57) | P2RY12CTSBCASR | |
| SCHEMBL18023284 | 0.82 | KDM1A (0.57) | ALDH1A1P2RY12TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021128-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES INC. (US) | 2015-02-12 | — | — | WO | disclosed |