Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.54 |
| ▸ | MC5R | P33032 | 1/20 | 0.54 |
| ▸ | MC3R | P41968 | 1/20 | 0.54 |
| ▸ | MC1R | Q01726 | 1/20 | 0.54 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.53 |
| ▸ | PTH1R | Q03431 | 2/20 | 0.53 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 4/20 | 0.52 |
| ▸ | GLP1R | P43220 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973199 | 0.97 | CTSL (0.54) | CTSLCTSSCTSKCTSHMC4R | |
| SCHEMBL9347526 | 0.91 | CTSL (0.54) | CTSLCTSSCTSKCTSHMC4R | |
| SCHEMBL29973495 | 0.89 | CTSL (0.56) | CTSLCTSSCTSKCTSHMC4R | |
| SCHEMBL31501133 | 0.86 | C5AR1 (0.53) | CTSLCTSSCTSKCTSHC5AR1 | |
| SCHEMBL29641069 | 0.85 | IL23R (0.58) | CTSLCTSSCTSKCTSHIL23R | |
| SCHEMBL29410268 | 0.85 | IL23R (0.62) | IL23RPTH1RC5AR1KEAP1CCKBR | |
| SCHEMBL30037155 | 0.85 | IL23R (0.62) | IL23RPTH1RC5AR1KEAP1CCKBR | |
| SCHEMBL29389186 | 0.85 | IL23R (0.62) | IL23RPTH1RC5AR1KEAP1CCKBR | |
| SCHEMBL10419744 | 0.84 | C5AR1 (0.51) | CTSLCTSSCTSKCTSHMC4R | |
| SCHEMBL29540499 | 0.84 | C5AR1 (0.58) | IL23RC5AR1KISS1RGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458449-B2 | Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same | NEW YORK UNIVERSITY (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150044189-A1 | HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME | NEW YORK UNIVERSITY | 2015-02-12 | — | — | US | disclosed |