Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.57 |
| ▸ | GLP1R | P43220 | 4/20 | 0.53 |
| ▸ | IL23R | Q5VWK5 | 5/20 | 0.53 |
| ▸ | GHSR | Q92847 | 4/20 | 0.53 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29461998 | 1.00 | C5AR1 (0.58) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29884974 | 1.00 | C5AR1 (0.58) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29641153 | 1.00 | C5AR1 (0.58) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29461985 | 0.96 | TUBB4A (0.58) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31501133 | 0.96 | C5AR1 (0.53) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29641170 | 0.95 | TUBB4A (0.57) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30132314 | 0.95 | TUBB4A (0.57) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29461979 | 0.95 | C5AR1 (0.56) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29540710 | 0.94 | C5AR1 (0.58) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29641105 | 0.94 | IL23R (0.57) | C5AR1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062752-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS | STEALTH BIOTHERAPEUTICS INC. (US) | 2026-03-05 | — | — | US | disclosed |
| US-12297502-B2 | Methods and compositions for detecting and diagnosing diseases and conditions | STEALTH BIOTHERAPEUTICS INC. (US) | 2025-05-13 | — | — | US | disclosed |
| US-20250109167-A1 | METHODS FOR THE TREATMENT OF MITOCHONDRIAL DISEASE | STEALTH BIOTHERAPEUTICS INC. (US) | 2025-04-03 | — | — | US | disclosed |
| US-20240108740-A1 | THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-04-04 | — | — | US | disclosed |
| US-20240100119-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-03-28 | — | — | US | disclosed |
| US-11931397-B2 | Methods and compositions for the treatment of Sengers syndrome | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20230398172-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY (US) | 2023-12-14 | — | — | US | disclosed |
| US-11628198-B2 | Methods for prevention and treatment of acute renal injury | CORNELL UNIVERSITY (US) | 2023-04-18 | — | — | US | disclosed |
| US-20230033758-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-02-02 | — | — | US | disclosed |
| US-11312993-B2 | Methods and compositions for detecting and diagnosing diseases and conditions | STEALTH BIOTHERAPEUTICS INC. (US) | 2022-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11628198-B2 | Methods for prevention and treatment of acute renal injury | ARG2, SERPINC1, ARG1 | C5AR1 220/4885TUBB4A 3566/4885TUBB 2953/4885 |
| US-20250109167-A1 | METHODS FOR THE TREATMENT OF MITOCHONDRIAL DISEASE | NLN, OAT, HAGH | C5AR1 4386/4885TUBB4A 1203/4885TUBB 785/4885 |
| US-20230398172-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | C5AR1 220/4885TUBB4A 3566/4885TUBB 2953/4885 |
| US-20240100119-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF FRIEDREICH'S ATAXIA | OAT, TFAM, OTC | C5AR1 3421/4885TUBB4A 1638/4885TUBB 1023/4885 |
| US-20240108740-A1 | THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF | S100A10, SPG11, TMSB10 | C5AR1 1698/4885TUBB4A 1756/4885TUBB 1446/4885 |
| US-20260062752-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS | ARG2, MTPN, TNNT2 | C5AR1 4318/4885TUBB4A 4185/4885TUBB 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.