Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10528373 | 0.79 | CES1 (0.67) | CES1SRCCES2TSHRDAO | |
| SCHEMBL1056586 | 0.79 | CES1 (0.67) | CES1SRCCES2TSHRDAO | |
| SCHEMBL454667 | 0.78 | CA2 (0.71) | CES1CES2ALDH1A1CA2NPSR1 | |
| SCHEMBL7907262 | 0.78 | CES1 (0.73) | CES1SRCCES2TSHRDAO | |
| SCHEMBL33083 | 0.78 | CES1 (1.00) | CES1CES2TSHRDAONAPRT | |
| Benzene SCHEMBL27672585 | 0.78 | CES1 (1.00) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL8780870 | 0.77 | CES1 (0.64) | CES1SRCCES2TSHRDAO | |
| Water SCHEMBL8534837 | 0.77 | CES1 (0.64) | CES1SRCCES2TSHRDAO | |
| SCHEMBL27972618 | 0.77 | CES1 (0.64) | CES1SRCCES2TSHRDAO | |
| SCHEMBL680607 | 0.77 | CES1 (0.57) | CES1SRCCES2TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120289670-A1 | Fluorinated Alkoxy-Imino Catalyst Components | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2012-11-15 | — | — | US | disclosed |
| US-20110312489-A1 | Fluorinated Alkoxy-Imino Catalyst Components | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-12-22 | — | — | US | disclosed |
| US-8026192-B2 | Fluorinated alkoxy-imino catalyst components | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-09-27 | — | — | US | disclosed |
| EP-2064218-B8 | FLUORINATED ALKOXY-IMINO CATALYST COMPONENTS | TOTAL PETROCHEMICALS RES FELUY (BE) | 2011-09-14 | — | — | EP | disclosed |
| EP-2064218-B1 | FLUORINATED ALKOXY-IMINO CATALYST COMPONENTS | TOTAL PETROCHEMICALS RES FELUY (BE) | 2011-04-20 | — | — | EP | disclosed |
| US-20100029472-A1 | Fluorinated Alkoxy-Imino Catalyst Components | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-02-04 | — | — | US | disclosed |
| EP-2064218-A1 | FLUORINATED ALKOXY-IMINO CATALYST COMPONENTS | Total Petrochemicals Research Feluy (BE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008031890-A1 | FLUORINATED ALKOXY-IMINO CATALYST COMPONENTS. | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-03-20 | — | — | WO | disclosed |
| EP-1900722-A1 | Fluorinated alkoxy-imino catalyst components | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312489-A1 | Fluorinated Alkoxy-Imino Catalyst Components | FLI1, INF2, FOS | CES1 4394/4885SRC 1037/4885CES2 2068/4885 |
| US-20100029472-A1 | Fluorinated Alkoxy-Imino Catalyst Components | FLI1, INF2, FOS | CES1 4394/4885SRC 1037/4885CES2 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.