Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 11/20 | 0.46 |
| ▸ | MMP9 | P14780 | 9/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16458406 | 0.87 | NPY5R (0.49) | ALDH1A1MMP2MMP9ADAMTS4NPY5R | |
| SCHEMBL16458405 | 0.87 | NPY5R (0.45) | ALDH1A1MMP2MMP9ADAMTS4NPY5R | |
| SCHEMBL12225850 | 0.84 | NPY5R (0.43) | MMP2MMP9ADAMTS4NPY5RF2 | |
| SCHEMBL12225905 | 0.70 | PSMB5 (0.43) | ALDH1A1MMP2MMP9ADAMTS4NPY5R | |
| SCHEMBL15195208 | 0.69 | MMP2 (0.48) | ALDH1A1MMP2MMP9ADAMTS4NPY5R | |
| SCHEMBL16459794 | 0.68 | NPY5R (0.51) | ALDH1A1MMP2MMP9ADAMTS4NPY5R | |
| SCHEMBL16459793 | 0.68 | NPY5R (0.47) | ALDH1A1MMP2MMP9ADAMTS4NPY5R | |
| SCHEMBL25217311 | 0.68 | ALDH1A1 (0.48) | ALDH1A1MMP2ADAMTS4ADAMTS5MAPT | |
| SCHEMBL16459707 | 0.68 | MMP2 (0.47) | ALDH1A1MMP2MMP9ADAMTS4NPY5R | |
| SCHEMBL15195203 | 0.68 | MMP2 (0.45) | ALDH1A1MMP2MMP9ADAMTS4NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140011998-A1 | DERIVATIVES OF 1-AMINO-2-CYCLOPROPYLETHYLBORONIC ACID | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011998-A1 | DERIVATIVES OF 1-AMINO-2-CYCLOPROPYLETHYLBORONIC ACID | PSMB6, PSMB5, PSMB1 | ALDH1A1 2471/4885MCL1 192/4885MMP2 4387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.