Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 11/20 | 0.43 |
| ▸ | MMP9 | P14780 | 9/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16458406 | 0.87 | NPY5R (0.49) | NPY5RMMP2MMP9ADAMTS4F2 | |
| SCHEMBL16458682 | 0.87 | ALDH1A1 (0.47) | NPY5RMMP2MMP9ADAMTS4F2 | |
| SCHEMBL12225850 | 0.84 | NPY5R (0.43) | NPY5RMMP2MMP9ADAMTS4F2 | |
| SCHEMBL16459707 | 0.83 | MMP2 (0.47) | NPY5RMMP2MMP9ADAMTS4F2 | |
| SCHEMBL16459793 | 0.82 | NPY5R (0.47) | NPY5RMMP2MMP9ADAMTS4F2 | |
| SCHEMBL19347782 | 0.80 | MMP2 (0.46) | NPY5RMMP2MMP9ADAMTS4F2 | |
| SCHEMBL19347775 | 0.79 | MMP2 (0.43) | NPY5RMMP2MMP9ADAMTS4F2 | |
| SCHEMBL19347783 | 0.76 | ADAMTS4 (0.47) | NPY5RMMP2MMP9ADAMTS4F2 | |
| SCHEMBL16460255 | 0.74 | MMP2 (0.50) | NPY5RMMP2MMP9ADAMTS4F2 | |
| SCHEMBL16458533 | 0.73 | MMP2 (0.51) | NPY5RMMP2MMP9ADAMTS4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140011998-A1 | DERIVATIVES OF 1-AMINO-2-CYCLOPROPYLETHYLBORONIC ACID | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011998-A1 | DERIVATIVES OF 1-AMINO-2-CYCLOPROPYLETHYLBORONIC ACID | PSMB6, PSMB5, PSMB1 | NPY5R 4010/4885MMP2 4387/4885MMP9 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.