SCHEMBL16458740

SCHEMBL16458740

O=CCC(C(=O)c1cccs1)c1cccs1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.57
CES1 P23141 2/20 0.57
KEAP1 Q14145 1/20 0.57
RAB9A P51151 4/20 0.43
NPC1 O15118 3/20 0.43
ALDH1A1 P00352 3/20 0.43
POLB P06746 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
KMT2A Q03164 1/20 0.43
DAO P14920 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
GSK3B P49841 1/20 0.41
CYP2C19 P33261 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
HDAC1 Q13547 1/20 0.40
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22721136 0.85 CES2 (0.54) CES2CES1KEAP1RAB9ANPC1
SCHEMBL11400057 0.82 CES2 (0.51) CES2CES1KEAP1RAB9ANPC1
SCHEMBL3309882 0.82 CYP2C19 (0.47) CES2CES1KEAP1RAB9ANPC1
SCHEMBL11271250 0.79 POLB (0.59) CES2CES1KEAP1RAB9ANPC1
SCHEMBL29636408 0.77 HPGD (0.39) CES2CES1KEAP1RAB9ANPC1
SCHEMBL29636391 0.76 MME (0.40) CES2CES1KEAP1RAB9ANPC1
SCHEMBL5776438 0.76 CES2 (0.62) CES2CES1KEAP1RAB9ANPC1
SCHEMBL28057486 0.75 CES2 (0.53) CES2CES1KEAP1RAB9ANPC1
SCHEMBL30416659 0.74 CTSK (0.37) CES2CES1KEAP1ALDH1A1SMN1; SMN2
SCHEMBL11167381 0.73 CES2 (0.44) CES2CES1KEAP1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9175328-B2 Electron transfer mediators for enzyme-based biosensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-03 US claimed
US-20140102896-A1 ELECTRON TRANSFER MEDIATORS FOR ENZYME-BASED BIOSENSOR INSTITUTE FOR RESEARCH & INDUSTRY COOPERATION, PNU (KR) 2014-04-17 US claimed
US-9175328-B2 Electron transfer mediators for enzyme-based biosensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-03 US disclosed
US-20140102896-A1 ELECTRON TRANSFER MEDIATORS FOR ENZYME-BASED BIOSENSOR INSTITUTE FOR RESEARCH & INDUSTRY COOPERATION, PNU (KR) 2014-04-17 US disclosed