Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.62 |
| ▸ | CES1 | P23141 | 2/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18108719 | 0.80 | CES2 (0.44) | CES2CES1KEAP1DAONPC1 | |
| SCHEMBL6250431 | 0.77 | CES2 (1.00) | CES2CES1KEAP1DAONPC1 | |
| SCHEMBL22721136 | 0.76 | CES2 (0.54) | CES2CES1KEAP1DAONPC1 | |
| SCHEMBL16458740 | 0.76 | CES2 (0.57) | CES2CES1KEAP1DAONPC1 | |
| SCHEMBL29951402 | 0.75 | RAB9A (0.51) | CES2CES1KEAP1DAONPC1 | |
| SCHEMBL22244933 | 0.75 | ALOX5 (0.41) | CES2CES1KEAP1NPC1RAB9A | |
| SCHEMBL29254348 | 0.75 | CES2 (0.40) | CES2CES1KEAP1DAONPC1 | |
| SCHEMBL1200971 | 0.75 | HPGD (0.41) | CES2CES1KEAP1NPC1RAB9A | |
| SCHEMBL27501702 | 0.75 | CES2 (0.40) | CES2CES1KEAP1DAOALDH1A1 | |
| SCHEMBL11400057 | 0.74 | CES2 (0.51) | CES2CES1KEAP1DAONPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358190-B1 | AMORPHOUS ORGANIC 1,3,2-DIOXABORINE LUMINOPHORES, METHOD FOR THE PRODUCTION AND USE THEREOF | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2006-04-26 | — | — | EP | disclosed |
| EP-1358190-A1 | AMORPHOUS ORGANIC 1,3,2-DIOXABORINE LUMINOPHORES, METHOD FOR THE PRODUCTION AND USE THEREOF | Siemens Aktiengesellschaft (DE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002064600-A1 | AMORPHOUS ORGANIC 1,3,2-DIOXABORINE LUMINOPHORES, METHOD FOR THE PRODUCTION AND USE THEREOF | SIEMENS AKTIENGESELLSCHAFT (DE) | 2002-08-22 | — | — | WO | disclosed |