Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16458296 | 0.88 | MAPK1 (0.31) | CYP2B6MAPK1 | |
| Hydrochloric Acid SCHEMBL16459241 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL16458099 | 0.81 | ESR1 (0.36) | ESR1ESR2CYP2B6MAPK1 | |
| Hydrochloric Acid SCHEMBL16459488 | 0.79 | ESR1 (0.34) | ESR1ESR2CYP2B6 | |
| Hydrochloric Acid SCHEMBL16458948 | 0.78 | ESR1 (0.33) | ESR1ESR2CYP2B6 | |
| Hydrochloric Acid SCHEMBL16458851 | 0.78 | ESR1 (0.33) | ESR1ESR2CYP2B6 | |
| Hydrochloric Acid SCHEMBL16458347 | 0.77 | KIF11 (0.34) | ESR2 | |
| Hydrochloric Acid SCHEMBL16458789 | 0.77 | ESR1 (0.39) | ESR1ESR2CYP2B6MAPK1 | |
| Hydrochloric Acid SCHEMBL16458142 | 0.75 | KCNN4 (0.32) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL16458319 | 0.75 | CYP1A2 (0.32) | ESR1ESR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140012056-A1 | METHOD FOR PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012056-A1 | METHOD FOR PRODUCING 1-HEXENE | AP2A1, AP1M1, ME1 | ESR1 452/4885ESR2 641/4885CYP2B6 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.