Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4863368 | 0.84 | ALDH1A1 (0.32) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL28986522 | 0.84 | GRIN2D (0.41) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL28986519 | 0.84 | GRIN2D (0.41) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL27031268 | 0.83 | CYP3A4 (0.33) | LMNACYP3A4 | |
| SCHEMBL12301913 | 0.81 | ALDH1A1 (0.33) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL29546719 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHR | |
| SCHEMBL12330817 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHR | |
| SCHEMBL10044939 | 0.80 | EGFR (0.33) | — | |
| SCHEMBL55735 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5836580 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307429-B1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO PERFUMERY CO LTD (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-20170367388-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-12-28 | — | — | US | disclosed |
| US-20170367388-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-12-28 | — | — | US | disclosed |
| US-9756872-B2 | Substituted butanol derivatives and their use as fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9756872-B2 | Substituted butanol derivatives and their use as fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9756872-B2 | Substituted butanol derivatives and their use as fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-09-12 | — | — | US | disclosed |
| US-20150245641-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
| US-20150245641-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
| US-20150245641-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
| US-9060535-B2 | Substituted butanol derivatives and their use as fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-06-23 | — | — | US | disclosed |
| US-9060535-B2 | Substituted butanol derivatives and their use as fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-06-23 | — | — | US | disclosed |
| US-9060535-B2 | Substituted butanol derivatives and their use as fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-06-23 | — | — | US | disclosed |
| US-20110217245-A1 | Substituted Butanol Derivatives And Their Use As Fragrance And Flavor Materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-09-08 | — | — | US | disclosed |
| US-20110217245-A1 | Substituted Butanol Derivatives And Their Use As Fragrance And Flavor Materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-09-08 | — | — | US | disclosed |
| US-20110217245-A1 | Substituted Butanol Derivatives And Their Use As Fragrance And Flavor Materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-09-08 | — | — | US | disclosed |
| EP-2307429-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | Takasago International Corporation (JP) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010002386-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-01-07 | — | — | WO | disclosed |
| US-7592362-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170367388-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | ACMSD, C1S, C5 | ALDH1A1 1081/4885TDP1 4134/4885LMNA 1301/4885 |
| US-20110217245-A1 | Substituted Butanol Derivatives And Their Use As Fragrance And Flavor Materials | ACMSD, C1S, C5 | ALDH1A1 1081/4885TDP1 4134/4885LMNA 1301/4885 |
| US-20150245641-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | ACMSD, C1S, C5 | ALDH1A1 1081/4885TDP1 4134/4885LMNA 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.