Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645899 | 0.84 | ALDH1A1 (0.33) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL28986519 | 0.81 | GRIN2D (0.41) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL28986522 | 0.81 | GRIN2D (0.41) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL12301913 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5836580 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TDP1TSHR | |
| SCHEMBL29546719 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHR | |
| SCHEMBL12330817 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHR | |
| SCHEMBL3681746 | 0.76 | LMNA (0.35) | ALDH1A1LMNATSHR | |
| SCHEMBL27899015 | 0.76 | SLC13A3 (0.36) | — | |
| SCHEMBL55735 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439266-B2 | Malononitrile compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-21 | — | — | US | disclosed |
| US-7439266-B2 | Malononitrile compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-21 | — | — | US | disclosed |
| US-20060004092-A1 | Malononitrile compound and use thereof pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-01-05 | — | — | US | disclosed |
| WO-2004020399-A1 | MALONONITRILE COMPOUND AND USE THEREOF AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004092-A1 | Malononitrile compound and use thereof pesticides | ME1, MAL2, ME3 | ALDH1A1 239/4885TDP1 4386/4885LMNA 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.