Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Cellobiose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 3/20 | 0.55 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.55 |
| ▸ | LGALS4 | P56470 | 3/20 | 0.55 |
| ▸ | IGF2R | P11717 | 2/20 | 0.49 |
| ▸ | AMY2A | P04746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | CA9 | Q16790 | 6/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cellobiose SCHEMBL2787564 | 1.00 | LGALS8 (0.55) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL5310426 | 0.97 | LGALS8 (0.55) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL11230654 | 0.93 | LGALS8 (0.49) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL22636942 | 0.92 | LGALS8 (0.49) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL11512625 | 0.91 | LGALS8 (0.54) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Maltose SCHEMBL8343753 | 0.91 | LGALS8 (0.54) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Maltose SCHEMBL8994870 | 0.90 | LGALS8 (0.53) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL18229206 | 0.90 | LGALS8 (0.58) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL18229209 | 0.90 | LGALS8 (0.58) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL23708014 | 0.89 | LGALS8 (0.61) | LGALS8LGALS3LGALS4IGF2RAMY2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475759-B2 | Tigecycline crystalline hydrate and preparation method therefor and use thereof | HU LIFANG (CN) | 2016-10-25 | — | — | US | disclosed |
| US-20140107357-A1 | TIGECYCLINE CRYSTALLINE HYDRATE AND PREPARATION METHOD THEREFOR AND USE THEREOF | HU LIFANG (CN) | 2014-04-17 | — | — | US | disclosed |