Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cellobiose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.46 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.58 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.58 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | AMY2A | P04746 | 3/20 | 0.52 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GJA1 | P17302 | 1/20 | 0.47 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | IGF2R | P11717 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cellobiose SCHEMBL18229206 | 1.00 | LGALS8 (0.58) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| Cellobiose SCHEMBL18229204 | 0.98 | LGALS8 (0.57) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| Cellobiose SCHEMBL18229205 | 0.98 | LGALS8 (0.57) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| Maltotriose SCHEMBL28275648 | 0.97 | LGALS8 (0.58) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| Cellobiose SCHEMBL5701237 | 0.97 | LGALS8 (0.58) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| Maltotriose SCHEMBL24202675 | 0.97 | LGALS8 (0.61) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| Cellobiose SCHEMBL24662526 | 0.97 | LGALS8 (0.61) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| Cellobiose SCHEMBL23752618 | 0.97 | LGALS8 (0.61) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| Cellobiose SCHEMBL24202679 | 0.97 | LGALS8 (0.61) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| Cellobiose SCHEMBL21206262 | 0.97 | LGALS8 (0.61) | LGALS8LGALS3LGALS4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294074-B1 | FAST-DISSOLVING CO-CRYSTALLINE LACTOSE | NESTLE SA (CH) | 2020-04-22 | — | — | EP | disclosed |
| EP-3294074-A1 | FAST-DISSOLVING CO-CRYSTALLINE LACTOSE | Nestec S.A. (CH) | 2018-03-21 | — | — | EP | disclosed |
| WO-2016180776-A1 | FAST-DISSOLVING CO-CRYSTALLINE LACTOSE | NESTEC S.A. (CH) | 2016-11-17 | — | — | WO | disclosed |