SCHEMBL1646292

SCHEMBL1646292

CCSSc1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
CYP2A6 P11509 1/20 0.38
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
FBP1 P09467 4/20 0.37
NOS3 P29474 2/20 0.37
NOS1 P29475 2/20 0.37
NOS2 P35228 2/20 0.37
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
TSHR P16473 1/20 0.37
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP1A2 P05177 1/20 0.36
RECQL P46063 1/20 0.36
ALDH1A1 P00352 1/20 0.35
PTGIR P43119 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3895678 0.78 TDP1 (0.40) LMNARAB9ANPC1MAPTNPSR1
SCHEMBL775698 0.76 FBP1 (0.37) LMNAHTTFBP1ALDH1A1MAOA
SCHEMBL28243162 0.76 FBP1 (0.32) FBP1
SCHEMBL1646234 0.76 MAOA (0.41) LMNACYP2A6MAPTFBP1MEN1
SCHEMBL1646155 0.76 TSHR (0.38) FBP1TSHR
SCHEMBL22042812 0.76 SLC6A4 (0.37) LMNAHTTFBP1KMT2ATSHR
SCHEMBL162332 0.76 LMNA (0.57) LMNACYP2A6RAB9ANPC1MAPT
SCHEMBL1647142 0.76 FBP1 (0.45) MAPTFBP1NOS3NOS1NOS2
SCHEMBL575878 0.75 SMN1; SMN2 (0.55) MAPTFBP1NOS3NOS1NOS2
SCHEMBL434310 0.75 MEN1 (0.47) LMNACYP2A6RAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed