Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 9/20 | 0.63 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.63 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.63 |
| ▸ | CDK1 | P06493 | 6/20 | 0.63 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.63 |
| ▸ | MGMT | P16455 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20007219 | 0.83 | CDK2 (0.45) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL16463883 | 0.80 | TSHR (0.39) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL2056438 | 0.79 | CCNA2 (0.67) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL16463323 | 0.78 | CDK2 (0.66) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL4454204 | 0.78 | CDK2 (0.66) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL16465651 | 0.78 | CDK2 (1.00) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL16464949 | 0.76 | CDK2 (1.00) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL16462614 | 0.74 | TSHR (0.42) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL16464209 | 0.74 | CDK2 (0.73) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL7988070 | 0.71 | CDK2 (0.77) | CDK2CCNA2CCNA1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906191-B1 | HAIR DYE CONTAINING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2018-03-28 | — | — | EP | disclosed |
| EP-2906191-B1 | HAIR DYE CONTAINING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2018-03-28 | — | — | EP | disclosed |
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | disclosed |
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | disclosed |
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | disclosed |
| EP-2906191-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | Henkel AG&Co. KGAA (DE) | 2015-08-19 | — | — | EP | disclosed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | disclosed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | disclosed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | disclosed |
| WO-2014056760-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2014-04-17 | — | — | WO | disclosed |
| WO-2014056760-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2014-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | KRT18, DPYD, DHFR | CDK2 671/4885CCNA2 550/4885CCNA1 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.