Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 18/20 | 0.45 |
| ▸ | CDK1 | P06493 | 11/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 11/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 11/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.45 |
| ▸ | MGMT | P16455 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463170 | 0.83 | CDK2 (0.63) | CDK2CDK1CCNA2CCNA1CCNB1 | |
| SCHEMBL20011580 | 0.65 | CDK2 (0.38) | CDK2CDK1CCNA2CCNA1CCNB1 | |
| SCHEMBL16482236 | 0.65 | TLR8 (0.44) | CDK2CDK1CCNA2CCNA1CCNB1 | |
| SCHEMBL16463883 | 0.63 | TSHR (0.39) | CDK2CDK1CCNA2CCNA1CCNB1 | |
| SCHEMBL2056438 | 0.63 | CCNA2 (0.67) | CDK2CDK1CCNA2CCNA1CCNB1 | |
| SCHEMBL16463323 | 0.62 | CDK2 (0.66) | CDK2CDK1CCNA2CCNA1CCNB1 | |
| SCHEMBL16464739 | 0.62 | CHRNB2 (0.35) | — | |
| SCHEMBL16465651 | 0.62 | CDK2 (1.00) | CDK2CDK1CCNA2CCNA1CCNB1 | |
| SCHEMBL16463766 | 0.60 | HTR1B (0.38) | KMT2A | |
| SCHEMBL11701544 | 0.60 | P2RX3 (0.34) | CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906191-B1 | HAIR DYE CONTAINING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2018-03-28 | — | — | EP | disclosed |