Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.91 |
| ▸ | MAPT | P10636 | 3/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.91 |
| ▸ | MEN1 | O00255 | 1/20 | 0.91 |
| ▸ | GAA | P10253 | 1/20 | 0.91 |
| ▸ | PKM | P14618 | 1/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.91 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.91 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.41 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.41 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.41 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.41 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.41 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399808 | 0.95 | MAPT (1.00) | ALDH1A1MAPTKDM4EMEN1GAA | |
| Bromide SCHEMBL10683199 | 0.93 | MAPT (0.95) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL1535914 | 0.81 | MAPT (0.59) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL5837186 | 0.81 | KMT2A (0.59) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL21155841 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL18830558 | 0.78 | MEN1 (0.57) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL11347157 | 0.75 | MEN1 (0.67) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL6568351 | 0.75 | MAPT (0.67) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL24869713 | 0.72 | DRD1 (0.69) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL5557727 | 0.72 | KDM4E (0.55) | ALDH1A1MAPTKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314240-B2 | Sulfonamide compounds or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20110201616-A1 | SULFONAMIDE COMPOUNDS OR SALTS THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2305641-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-4367235-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-04 | — | — | US | disclosed |
| EP-0000784-A1 | 4-Hydroxy-2-benzimidazolinone derivatives, process for their preparation and their use in medicaments | Roche Diagnostics GmbH (DE) | 1979-02-21 | — | — | EP | disclosed |
| US-4110246-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-08-29 | — | — | US | disclosed |
| US-3985763-A | DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201616-A1 | SULFONAMIDE COMPOUNDS OR SALTS THEREOF | PTGER1, PTGER2, GPER1 | ALDH1A1 614/4885MAPT 4794/4885KDM4E 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.