Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399808 | 0.84 | MAPT (1.00) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| Bromide SCHEMBL10683199 | 0.82 | MAPT (0.95) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5606122 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5605839 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1646406 | 0.79 | ALDH1A1 (0.91) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5605453 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13732876 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5604970 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8666045 | 0.75 | CDC25B (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6056932 | 0.72 | CDC25B (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512848-B1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-11-18 | — | — | EP | disclosed |
| US-20190214574-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190214574-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | CYCS, CYP3A4, CYP2E1 | ALDH1A1 506/4885MAPT 2010/4885MEN1 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.