Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5682 | 0.97 | — | — | |
| SCHEMBL28643323 | 0.93 | — | — | |
| Biphenyl SCHEMBL27169703 | 0.88 | ALDH1A1 (0.53) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL31543788 | 0.85 | MAOA (0.50) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Anthracene SCHEMBL28066631 | 0.83 | HSD17B10 (0.41) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Acetaldehyde SCHEMBL27823848 | 0.81 | HPGD (0.39) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL22219420 | 0.79 | ALDH1A1 (0.50) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL8018881 | 0.79 | ALDH1A1 (0.50) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Hexane SCHEMBL17505033 | 0.79 | LTA4H (0.39) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Toluene SCHEMBL10384287 | 0.77 | ACHE (0.58) | HPGDMAPTSMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868714-B2 | Pyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY (JP) | 2018-01-16 | — | — | US | disclosed |
| EP-2906557-B1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-10-01 | — | — | US | disclosed |
| EP-2906557-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014058037-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | CBR3, NOTUM, DDT | HPGD 1690/4885MAPT 4413/4885SMN1; SMN2 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.