Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16468157 | 0.90 | MEN1 (0.53) | CASRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16467944 | 0.90 | MEN1 (0.42) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL16467951 | 0.88 | OPRK1 (0.40) | CASRMEN1KMT2AOPRK1RECQL | |
| SCHEMBL16467914 | 0.82 | ALDH1A1 (0.52) | CASRMEN1KMT2AALDH1A1OPRK1 | |
| SCHEMBL16468155 | 0.80 | PTGES (0.38) | KMT2AALDH1A1OPRK1PTGESNPC1 | |
| SCHEMBL16468270 | 0.80 | OPRK1 (0.39) | OPRK1PTGESLMNAHSD11B1KDM4E | |
| SCHEMBL16468258 | 0.79 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16468455 | 0.79 | PTGES (0.41) | OPRK1RECQLPTGESLMNAPKM | |
| SCHEMBL15265423 | 0.79 | MAOA (0.53) | L3MBTL1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16468252 | 0.78 | PTGES (0.44) | MEN1KMT2AL3MBTL1PTGESPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150051257-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | ADAMED SP. ZO.O (PL) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051257-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | AQP4, BCL6, STS | CASR 3812/4885MEN1 2136/4885KMT2A 896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.