SCHEMBL16470286

SCHEMBL16470286

CC(C)OC(=O)c1ccc(N2CSc3ccccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.49
CD274 Q9NZQ7 1/20 0.49
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
CA14 Q9ULX7 2/20 0.45
ALDH1A1 P00352 7/20 0.45
TSHR P16473 1/20 0.45
BCHE P06276 1/20 0.45
NPC1 O15118 5/20 0.44
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
RECQL P46063 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27992906 0.80 ALDH1A1 (0.44) CA12CA1CA2CA9ALDH1A1
SCHEMBL16470234 0.74 NPC1 (0.39) ALDH1A1TSHRBCHENPC1RAB9A
SCHEMBL11995114 0.73 SIGMAR1 (0.39) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL701832 0.71 CA12 (0.83) PDCD1CD274CA12CA1CA2
SCHEMBL16470166 0.70 TSHR (0.43) ALDH1A1TSHRRAB9ASMN1; SMN2LMNA
SCHEMBL16470372 0.70 LMNA (0.40) BCHELMNAL3MBTL1MEN1KMT2A
SCHEMBL16469856 0.70 MYC (0.51) ALDH1A1TSHRBCHESMN1; SMN2LMNA
Benzoic Acid 1-Methylethyl Ester SCHEMBL96918 0.69 PDCD1 (0.78) PDCD1CD274CA12CA1CA2
Benzoic Acid 1-Methylethyl Ester SCHEMBL27592410 0.69 PDCD1 (0.78) PDCD1CD274CA12CA1CA2
SCHEMBL28761675 0.69 CA12 (0.79) PDCD1CD274CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9829605-B2 Polarized film, optical film, and image display device NITTO DENKO CORPORATION (JP) 2017-11-28 US disclosed
US-20160152002-A1 TRANSPARENT CONDUCTIVE LAMINATED FILM, METHOD FOR MANUFACTURING SAME, AND TOUCH PANEL NITTO DENKO CORPORATION (JP) 2016-06-02 US disclosed
US-20150152299-A1 ACTIVE ENERGY RAY CURABLE ADHESIVE COMPOSITION, POLARIZING FILM AND METHOD FOR PRODUCING SAME, OPTICAL FILM AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-06-04 US disclosed
US-20150116817-A1 ACTIVE ENERGY RAY CURABLE ADHESIVE COMPOSITION, POLARIZING FILM AND METHOD FOR PRODUCING SAME, OPTICAL FILM AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-04-30 US disclosed
US-20150049380-A1 POLARIZED FILM, OPTICAL FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-02-19 US disclosed